The research progress of blood-oxygen-level dependent MR imaging in breast cancer：oxygen metabolism under hypoxic status and curative effect evaluation
LUO Xiaoyu
TANG Guangyu
Abstract：It has a clinical relevance to assess hypoxic metabolism and microvascular maturity in breast cancer. Being widely used in functional studies of brain blood-oxygen-level dependent contract functional magnetic resonance imaging (BOLD-fMRI) can assess the oxygenation and the maturity of the neovascularization within the lesions through the changes in the R2*value under the resting state and the△R2*value under the task state. We may also monitor the hypoxia status within the microenvironment of a tumour and develop a specialised and individualized treatment program to improve the cure rate of breast cancer and reduce mortality rate. Here, we summarized the BOLD-fMRI application status on assessment of oxygen metabolism under hypoxic status in breast cancer, vascular maturity and curative efficacy assessments.
Keywords：Breast cancerBlood oxygen level-dependentFunctional magnetic resonance imagingLack of oxygen metabolismCurative effect evaluation
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 126-130 )