The application of water channel protein theory in disease diagnosis
DU Ming
XIN Jun
ZHAO Zhoushe
GUO Qiyong
Abstract：The aquaporins (AQPs) are widely distributed in the cells, mediating the transport of water molecules on different types of cell membrane. They are closely related to human normal physiological activities and disease. With the theory of water channel protein in the disease diagnosis, medicine has huge development potential. PET imaging with positron nuclide labeling tracer and MR water molecules diffusion-weighted with different and high b values can show distribution and the expression level of AQPs. AQP molecular imaging technique is of important value not only for the early disease diagnosis but also for the individualized treatment.
Keywords：AquaporinMagnetic resonance imagingDiffusion weighted imagingMolecular imagingMolecular therapy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 58-61 )