Comparison between MRI and bone scintigraphy in detecting bone metastasis of prostate cancer
Abstract：Objective To compare the value between MRI and bone scintigraphy in detecting bone metastasis of prostate cancer, then choose the best noninvasive way to make a accurate staging. Methods and Materials A retrospective study of 252 cases, pathology proved prostate cancer from 2011 January to 2013 June, age range 57-88 years, mean age 73 ± 7.98 years. The sensitivities, specifilities, accuracies, values of PPV and NPV of MRI and Bone Scintigraphy in detecting bone metastasis of prostate cancer were calculated. Results Fifty-four patients were diagnosed having bone metastasis (48 cases with osteoblastic bone metastasis, six cases with mixed metastasis), and 41 of 54 patients (80%) with bone metastasis of prostate cancer had PSA>50 ng/mL, while 182 of 198 patients (92%) without bone metastasis had PSA<50 ng/mL. The sensitivity, specifility, accuracy, PPV,and NPV of MRI in detecting bone metastasis of prostate cancer was 85.1%, 100%, 96.8%, 100%and 96.1%, respectively;while for bone scintigraphy was 92.5%, 84.3%, 86.1%, 61.7%and 97.6%, respectively. Conclusion MRI has higher specificity, accuracy, and PPV, while bone scintigraphy has higher sensitivity in detecting bone metastasis of prostate cancer. MRI and bone scintigraphy can provide complementary information and may help in staging prostate cancer accurately.
Keywords：Prostate cancerDiffusion weight imagingMagnetic resonance imagingBone scintigraphyBone metastasis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 5-8 )