The value of dynamic contrast-enhanced MRI in estimating adjacent bones’ and extraocular muscles’ involvement of orbital malignant neoplasm
YAN Shuo
WANG Jian
JI Xiaodong
GUO Yu
WU Tong
XIA Shuang
Abstract：Objective To evaluate characteristics of surrounding bone, extraocular muscles of orbital malignant neoplasm using dynamic contrast-enhanced MRI (DEC-MRI). Methods The pattern of time-intensity curve (TIC) and quantitative parameters (Ktrans, ve, and iAUC) of DCE-MRI for 17 cases were studied retrospectively. All of the cases were diagnozed pathologically between Dec. 2010 and May 2014. Differences in quantitative parameters among orbital malignant neoplasm, surrounding involved structures and edematous structures were analyzed using Kruskal-Wallis test and Mann-Whitney U test. Pearson and Spearman correlation coefficient were calculated to evaluate the correlation between parameters of involved structures and neoplasm, and between edematous structures and neoplasm, retrospectively. Results ① High consistency in TIC were detected between involved structures and orbital malignant neoplasm. TIC of type-Ⅲwas a sign of involvement.②Correlation coefficients of Ktrans, ve, and iAUC between involved bones and neoplasm were 0.849, 0.790, and 0.641, respectively (P<0.05). Values of Ktrans, ve, and iAUC of bone edema were significantly smaller than the values of the neoplasm (P<0.05), without correlations between them (P>0.05).③Correlation coefficients of Ktrans and iAUC between involved extraocular muscles were 0.830 and 0.692, respectively (P<0.05). Values of Ktrans and iAUC of edematous muscles were significantly smaller than the values of the neoplasm (P<0.05), without correlations between them (P>0.05). Conclusion DCE-MRI could be helpful in the diagnosis of structures’ involvement and is an important complement of conventional MRI.
Keywords：Dynamic contrast-enhancedMagnetic resonance imagingOrbitMalignant neoplasm
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1-4 )