Progress on quantitative dynamic contrast-enhanced MRI in osteoporosis
ZHU Jingqi
TANG Guangyu
Abstract：Osteoporosis (OP) is a skeletal disease characterized by loss of bone strength, leading to an increased susceptibility to fractures. Microvessel reduction and microcirculatory disturbance are important factors of the genesis and progression of OP. Diagnostic imaging is of critical importance in identifying individuals at risk for OP and also in monitoring response to treatment. Quantitative dynamic contrast-enhanced MRI (DCE-MRI) is a noninvasive method to evaluate the characteristics of bone marrow microcirculation by gadolinium contrast agents. This paper mainly introduces the basic principles of DCE-MRI and the progress of bone marrow perfusion of OP with DCE-MRI.
Keywords：OsteoporosisMicrocirculationBone marrowPerfusionDynamic contrast-enhanced MRI
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 347-350 )