Advancements in Research on MicroRNAs Related to Insulin Resistance in Polycystic Ovary Syndrome
JIA Sheng-xiao
SUN Miao
KUANG Hong-ying
XU Bo-ya
Abstract：Insulin resistance(IR)characterizes not only a universal clinical feature of polycystic ovary syndrome(PCOS),but also serves a significant role in its pathophysiology.PCOS and IR are closely related and mutually cause each other.The interaction between IR and PCOS creates a detrimental cycle.There was substantial progress in the study of microRNAs(miRNAs)roles in PCOS-linked metabolic disturbances.The degree of miRNAs expression is intrinsically associated with PCOS-IR.In this paper,we discuss the miRNAs-related etiopathogenesis of PCOS-IR.
Keywords：Polycystic ovary syndromeMicroRNAsInsulin resistancePhosphatidylinositol 3-kinasesProto-oncogene proteins c-aktInsulin receptor substrate proteins
Publication Date：2025-01-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 59-64 )