Potential Application of Tanshinone in the Treatment of Polycystic Ovary Syndrome and Mechanism
LI An-qi
ZHU Meng-yi
WANG Yu
GAO Jing-shu
WU Xiao-ke
Abstract：Tanshinone is a type of compound extracted from the traditional Chinese medicine Salvia miltiorrhiza,and it has received considerable attention due to its anti-inflammatory,antioxidant,and anti-cancer properties.Recent studies have suggested that tanshinone holds potential value in the treatment of polycystic ovary syndrome(PCOS).Tanshinone may effectively improve the insulin resistance,abnormal lipid metabolism,hyperandrogenemia,and chronic low-grade inflammation in PCOS patients by regulating hormone balance,enhancing insulin sensitivity,and reducing inflammatory responses.In addition,tanshinone can also improve ovulation disorders and ovarian dysfunction in PCOS patients.This article aims to review the research progress of tanshinone in the treatment of PCOS in recent years,in order to provide a theoretical reference for clinical practice and new drug development for PCOS.
Keywords：TanshinonePolycystic ovary syndromeMechanism of actionCryptotanshinoneTanshinon ⅡA
Publication Date：2024-11-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 494-500 )