HPV Transmission through Sperm and Its Impact on Early Embryonic Development
ZHAO An-qi
LIU Lin
TAN Xiao-fang
Abstract：Human papilloma virus(HPV)infection is one of the most common sexually transmitted diseases,which is associated with the development of tumors in multiple organs.In recent years,the impact of HPV infection on fertility has garnered significant attention,particularly its vertical transmission through germ cells and potential effects on early embryonic development.Studies have shown that HPV infection may affect sperm quality,leading to infertility,and may also interfere with embryonic development,increasing the risk of spontaneous abortion and adversely affecting pregnancy outcomes in assisted reproductive technology.This review summarizes the research progress on the vertical transmission of HPV through sperm cells and its impact on early embryonic development,to deeply understand the potential threat of HPV to reproductive health and to provide references for clinical practice and further research.
Keywords：SpermatozoaEmbryonic developmentAbortionspontaneousReproductive techniquesassistedInfectious disease transmissionverticalHuman papilloma virus
Publication Date：2024-07-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 328-331 )