Study Progress of Postovulatory Oocyte Aging
YANG Ji-hong
WANG Hui
Abstract：The oocyte aging is related to many adverse factors,in which oxidative stress and mitochondrial dysfunction lower the quality of oocyte and affect further development.Postovulatory aging (POA),one type of oocyte aging,is more common in the in vitro culture of oocyte,which causes not only dysembryoplasia and poor oocyte quality but also the reduced pregnancy rate and the increased birth defects.Oxidative stress is the essential trigger factor of POA,which may influence the oocyte quality and embryonic developmental potential via the activated apoptosis-related pathways.This paper summarizes the factors of POA,oxidative stress and different antioxidants for delaying POA.
Keywords：OocytesCell agingOxidative stressAntioxidantsEmbryonic development
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 66-70 )