Relationship between Visfatin and Gestational Metabolic Syndrome
ZHANG Yan-hong
Abstract：Gestational metabolic syndrome (GMS) is a cluster of multiple metabolic disorders during pregnancy,including abnormal body mass,dysglycemia,dyslipidemia and hypertension,which will lead to adverse pregnancy outcomes such as gestational diabetes mellitus (GDM),preeclampsia,fetal intrauterine growth restriction and so on.The incidence of GMS increases yearly.At present,the research of GMS is mainly focused on the diagnostic criteria and risk factors.However,the mechanism of GMS and its prevention strategy are lack of further research.Visfatin,a kind of adipocytokines,is mainly expressed in and secreted from visceral adipose tissue.Visfatin plays a role in the metabolism of glucose and lipid.It was found that visfatin participated in insulin resistance,inflammatory reaction,cell apoptosis,atherosclerosis and vascular endothelial injury.Recent studies have indicated that visfatin is closely related to the pathogenesis of GMS.
Keywords：PregnancyMetabolic syndrome XNicotinamide phosphoribosyltransferaseDiabetesgestationalPre-eclampsia
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 168-171 )