Anti-Mullerian Hormone and Male Reproduction-related Diseases
WANG Yan-fei
HU Rong
Abstract：Anti-Mullerian hormone (AMH), also known as Mullerian inhibiting hormone (MIS), was first discovered in the male fetus. AMH plays an important role in the male sexual differentiation by inhibiting Mullerian's development. Recent studies showed that AMH had more extensive application in male reproduction-related areas, mainly in the following five aspects: ① AMH can be used to diagnose whether those patients with hermaphroditism have male gonads, the sensitivity of serum AMH is higher than the Y chromosome. Meanwhile, AMH is a better markers in assessing the testicular function of adolescent. ② Compared with serum AMH, seminal AMH was significantly associated with spermatogenesis, and positively correlated with semen quality. Seminal AMH is specific marker to identify obstructive and non-obstructive azoospermia. ③ Seminal plasma AMH is a good index for predicting the recovery rate of the cryopreserved semen in asthenozoospermic men. ④Seminal AMH can be used to predict the outcome of recombinant human follicle-stimulating hormone treatment in men with idiopathic infertility. ⑤ Seminal AMH is one of the most specific biomarkers to assess male fertility of cancer patients after chemotherapy and radiotherapy.
Keywords：Anti-Mullerian hormoneInfertilitymaleReproductive health services
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 49-52 )