Fallopian Interstitial Pregnancy after Assisted Reproductive Technology:10 Cases Report

ZHANG Yuan; SHU Li; CHAI De-chun; DING Wei; MAO Yun-dong; WANG Wei; LIU Jia-yin

Abstract：Objective: This is ten cases report of the interstitial pregnancy after assisted reproductive technology (ART). Methods:Ten cases of the interstitial pregnancy after IVF/ICSI-ET in our center, from July 2011 to July 2013, were retrospectively analyzed. Clinical features and related risk factors were summarized. Results:Ten patients aged (32.9±3.7)years, with the tubal-related operation history, accepted IVF/ICSI treatment due to their tubal factors. Four cases had a history of ectopic pregnancy. Nine patients had been transferred 2 embryos in their ART cycles,and only 1 case transfered a single embryo. As for clinical manifestations,6 cases were firstly suspected for ectopic pregnancy by B ultrasound, 1 case suffered from abdominal pain ,1 case had a small amount of vaginal bleeding,and the other 2 cases were complained of abdominal pain and vaginal bleeding. After diagnosed, eight patients underwent direct operation,one case successfully received MTX treatment while another one case underwent operation after her unsuccessful MTX treatment. Conclusions:The interstitial pregnancy after IVF/ICSI was possibly related to abnormal function of fallopian tube after the tubal-related operation,especially tube resection or the proximal tubal occlusion. The number of transferred embryos should be controlled in those IVF/ICSI patients with high-risk factors,while B ultrasound monitoring after transplantation and health education should be added so as to reduce the adverse outcome of the interstitial pregnancy after ART.