MicroRNA and Cervical Cancer
LI Pu
LIU Jun-yan
KONG Fan-ming
YIN Li-rong
Abstract：MicroRNA (miRNA), a class of endogenous small non-coding regulatory RNAs, regulate the expression of target genes by pairing with its 3′untranslated regions (3′UTR) to induce the inhibited translation or mRNA degression. Mature miRNA may interfere with multiple biological processes involved in tumorigenesis such as cell proliferation, cell cycle, apoptosis, angiogenesis, invasion and metastasis. Multiple studies showed that the aberrant expression of miRNA, as novel potential makers, could provide numerous promising merits in diagnostic, pathological and therapeutic targets in cervical cancer.
Keywords：MicroRNAsUterine cervical neoplasmsCarcinomaDiagnosisDrug resistanceneoplasm
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 297-300 )