Effects of Different Criteria of hCG Administration on IVF/ICSI-ET Outcomes
LI Yan-hui
GAO Ying
GENG Yu-hong
CHEN Li-juan
LIU Lin
CHEN Chun-yan
Abstract：Objective:To explore the effects of two criteria of hCG administration on the clinical outcomes of IVF/ICSI-ET. These criteria were individually based on the follicle diameter and the follicle symmetry. Methods:It′s a prospective randomized study in our hospital reproductive center. IVF/ICSI-ET patients were randomly divided into two groups from Jan 2013 to Mar 2013. The criterion of hCG administration in Group A was based on the follicle diameter,while Group B on the follicle symmetry. Clinical and laboratory outcomes were then compared. Results:The average days of Gn, serum levels of progesterone and estradiol on the hCG day,the average number of matured eggs, and the rate of matured oocytes of group B were significantly higher than those of group A(P<0.05). There was not significant difference in the numbers of frozen embryos and good quality embryos between the two groups. However,the clinical pregnancy rate of group B was significantly lower than that of group A (42.19% vs. 54.22%, χ2=4.18,P=0.04), and the incidence of OHSS in group B significantly higher than that of group A(10.77%vs. 5.86%,χ2=4.07,P=0.04). Conclusions:The criterion based on the uniform size of follicular is not superior to the traditional criterion focused on the dominant follicle size in the efficacy and safety of IVF/ICSI-ET treatment.
Keywords：Chorionic gonadotropinFertilization in vitroSperm injectionsintracytoplasmicEmbryo transferSuperovulationPregnancy outcome
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 232-235 )