Etiology of Premature Ovarian Failure
CHEN Bei-li
CAO Yun-xia
Abstract：Premature ovarian failure (POF) is defined as the recession of ovarian function in women under the age of 40 years. The lost fertility and the lowered level of estrogen caused by POF are two factors affected reproductive health and life quality. And the morbidity is tending towards younger women in recent years. The etiological factors and pathogenesis of POF are extremely heterogeneous,involving genetic factors,immune factors,iatrogenic factors,metabolic factors,environmental factors and infection. This review discussed the etiology of POF.
Keywords：Ovarian failureprematureChromosome aberrationsAutoimmune diseasesIatrogenic factors
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 339-343 )