Transient Neonatal Myasthenia Gravis of Maternal Origin:A Case Report
WANG Peng-yuan
YI Feng-xin
CHI Yun-qian
ZHANG Zi-han
WANG Yun-he
ZHANG Xing-ying
HAO Wei
Abstract：Transient neonatal myasthenia gravis(TNMG)has an insidious onset,and its clinical manifestations are non-specific,making it easily misdiagnosed.It mainly occurs as a complication of maternal myasthenia gravis(MG).A case of a child with maternal TNMG is reported.The main manifestations were dyspnea,hypotonia,dysphagia,and a weak cry.The child was positive for acetylcholine receptor(AChR)antibodies.Based on the clinical manifestations and the mother's history of MG,the child was diagnosed with TNMG.After comprehensive treatment including mechanical ventilation,intravenous injection of human immunoglobulin,pyridostigmine bromide,and anti-infection therapy,the child's symptoms gradually improved.The child was cured and discharged on the 30th day after admission.During the follow-up until 6 months of age,the child's growth and development were normal.Early identification of TNMG is crucial.After individualized comprehensive intervention,the prognosis of most patients is good.
Keywords：InfantnewbornMyasthenia gravisneonatalReceptorscholinergicDiagnosisTherapyPrognosis
Publication Date：2026-02-15
Online Publishing Date：2026-03-24(First online date of this platform, not the publication date of the document)
Pages：4( 117-120 )