Clinical Application of Indocyanine Green Tracing of Sentinel Lymph Nodes in Early Cervical Cancer
CHAI Ling-na
LI Yan-li
SHI Jie
GAO Han
OUYANG Xi-yan
CHENG Shi-yu
Abstract：Cervical cancer is one of the malignant tumors that threaten women's health.The traditional surgical approach typically involves systemic lymph node dissection,which may lead to increased postoperative complications and affect the quality of life of patients.Sentinel lymph node biopsy(SLNB)technology aims to assess the lymph node metastasis status of patients and reduce unnecessary lymph node dissection for some patients with negative sentinel lymph node(SLN),thereby reducing surgical trauma.Indocyanine green(ICG),as a fluorescent tracer,has shown high sensitivity and specificity in SLNB for early cervical cancer,with a detection rate superior to that of biological dyes,carbon nanoparticles,and radioactive isotopes.It is currently one of the most commonly used tracers.Due to its limited tissue penetration,further research should focus on the clinical transformation of ICG combined with carrier technology to overcome the limitations of existing techniques.This article aims to provide a comprehensive review of the application of ICG-traced SLN in early cervical cancer,providing a reference to promote the clinical application of SLNB technology.
Keywords：Sentinel lymph nodeSentinel lymph node biopsyIndocyanine greenUterine cervical neoplasmsTracer
Publication Date：2025-04-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 175-179 )