Research Progress on the Relationship between Subclinical Hypothyroidism in Pregnancy and Hypertensive Disorders of Pregnancy
HU Min-hui
LIU Rui-xia
ZHAO Rong
YIN Cheng-hong
Abstract：Subclinical hypothyroidism(SCH)is the most common thyroid diseases during pregnancy.The vascular endothelial function injury and autonomic nervous dysfunction in SCH patients may increase the risk of cardiovascular diseases.Hypertensive disorders of pregnancy(HDP)complicate pregnancy and lead to increased rates of adverse pregnancy outcomes and mortality for both mothers and fetuses.Studies have found that SCH is associated with the increased incidence of HDP,but there is no uniform conclusion at present,and the potential benefits of levothyroxine(L-T4)treatment for HDP in SCH pregnant women are still controversial.This article reviews the impact of SCH on HDP during pregnancy and the effectiveness of L-T4 treatment,so as to standardize the clinical pregnancy management program and reduce the occurrence of perinatal adverse pregnancy outcomes in pregnant women and fetus.
Keywords：HypothyroidismHypertensionpregnancy-inducedThyrotropinPregnant womenLevothyroxine
Publication Date：2023-12-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 679-683 )