The Significance of Exosomes in the Development, Diagnosis and Treatment of Endometriosis
DONG Xiao-xiao
YU Xiao-hui
Abstract：Exosomes are vesicular structures that can stably exist in variety of body fluids,which can participate in transfering information and signal regulation among cells. The miRNAs and the proteins that they carry play an important role in many pathophysiological processes. It has received extensive attention due to its close relationship with the occurrence and development of many kinds of tumors and other diseases. Endometriosis is a disease that occurs in women of childbearing age, and has the characteristics of strong invasiveness, extensive pathological changes and easy recurrence. Exosomes, as an important signal regulators is involved in angiogenesis of endometriosis, proliferation and migration of ectopic endometrial cells, etc. It plays an important role in the occurrence and development of endometriosis, secondary lesions, and malignant transformation. However, the specific mechanism is not yet clear. This article reviews the role of exosomes in the development of endometriosis and provides new ideas for the early diagnosis and treatment of endometriosis.
Keywords：ExosomesEndometriosisMicroRNAsDiagnosisTherapy
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 283-286 )