The Anticoagulation Regimen in Pregnant Women with Mechanical Prosthetic Heart Valves
CUI Jin-shuai
LIN Hao
ZHANG Xiao-peng
GAO Bing-ren
Abstract：With the rapid development of cardiac surgery, more and more patients with heart valve disease can improve cardiac function and life quality through heart valve replacement. However, life-long anticoagulant therapy is required after mechanical heart valve replacement, and it is particularly important during pregnancy. Although mechanical heart valve replacement is associated with high-risk pregnancies, there is a lack of uniformity in the management of cardiac mechanical valve replacement. Individualized treatment is generally emphasizes. Anticoagulation during pregnancy after mechanical heart valve replacement is controversial. Warfarin can prevent the formation of maternal thrombus during pregnancy, but warfarin can affect the development of the fetus through the placenta. Heparin can not affect the development of the fetus through the placenta, but poorly monitor the convenience and prevent thrombosis. The anti-platelet drugs and the use of new drugs have not been further study. We reviews the choice of anticoagulants and maternal fetal outcomes in recent years in order to better serve the clinic.
Keywords：Heart valve prosthesis implantationPregnancyPregnant womenWarfarinAnticoagulantsHeparin
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 263-266 )