New Progress in Clinical Treatment of Locally Advanced Cervical Cancer
CAO Ying
SUN Wei
Abstract：Cervical cancer is one of malignant tumors which causes serious threat to women. Treatment for locally advanced cervical cancer(LACC)has being controversial because of its large lesions,operation difficulty and poor prognosis. Radical concurrent chemoradiotherapy,radical surgery and chemoradiotherapy plus hysterectomy are mainly recommended.In clinical treatments,due to the regional differences in radiotherapy levels and individual differences,the treatments of LACC still exhibit diversity. The therapeutic ratio of prophylactic semiextended field intensity-modulated radiation therapy is similar to conventional prophylactic extended-field radiotherapy,while the former reduces the incidence of toxicity.Chemoradiotherapy plus hyperthermia is well tolerated and causes no additional acute or long-term toxicity compared with chemoradiotherapy alone.There is no significant evidence indicates that para-aortic lymphadenectomy has a positive impact on overall survival in LACC,but it′s useful to predict the prognosis and related to better overall survival in patients with common iliac lymph node metastasis.Pelvic external beam radiotherapy with chemotherapy followed by type Ⅰextra-fascial hysterectomy can be a good alternative for patients who cannot have no access to successful intracavitary brachytherapy.
Keywords：Uterine cervical neoplasmsGynecologic surgical proceduresChemotherapyadjuvantLocally advanced cervical cancerConcurrent chemoradiotherapy
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 66-70 )