A Systematic Review of Surgical Evaluation Model for Advanced Epithelial Ovarian Cancer
LIU Chuan-zhong
LI Li
ZHAO Bing-bing
Abstract：Objective:To evaluate the accuracy of the evaluation models for advanced epithelial ovarian cancer (AEOC). Methods:Databases such as Pubmed, Cochrane Library, Medline, Embase and CNKI, VIP and CBM date were searched. Related literatures were published from the date of their establishment to March, 31, 2017. Reference articles of related articles were also researched. The searching language included Chinese and English. Meta-analysis was performed on studies meeting the inclusion criteria. Results:A total of 11 related studies were included. Meta-analysis showed that the total sensitivity and specificity of laparoscopy, CT and CA125 were 0.938, 0.816, 0.616 and 0.651, 0.830, 0.824 respectively. The total AUC of the corresponding model was calculated by calculating the area under the SROC curve. The AUC of the laparoscopy, CT and CA125 evaluation models were 0.949, 0.928 and 0.828, respectively. Conclusions:In all evaluation models, the CA125 evaluation model shows poor accuracy, while the CT evaluation model and the laparoscopic exploration evaluation model have higher accuracy, and the accuracy of laparoscopic exploration evaluation model is the highest. We expect more larger sample prospective clinical trials to validate the results of our study.
Keywords：Ovarian neoplasmsTreatment outcomeMeta -analysisAdvanced epithelial ovarian cancerOptimal debulking surgeryEvaluation model
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 524-528 )