Research Progress of Uterine Adenosarcoma
XING Juan
SHEN Zhen
ZHOU Ying
YU Ting
WU Da-bao
Abstract:Adenosarcoma is constituted by benign glandular epithelium and malignant stroma as a low degree of malignant potential of mixed tumor, mostly derived from the endometrium, occasionally can occur in the ovary or extrauterine tissue. Uterine adenosarcoma is a rare female genital tract malignant tumor, more common in postmenopausal women, lack of specific clinical symptoms. The most common clinical manifestations are vaginal bleeding, cervical prolapse and uterine enlargement. Early diagnosis of the disease is difficult. Ultrasound and MRI have a certain diagnostic value, and"cuff"-like structure is the postoperative pathological characteristics of the performance. The occurrence of uterine adenosarcoma may be associated with endometriosis, long-term estrogen exposure and other factors, but the specific pathogenesis is not yet clear. The main treatment of the disease for the unilateral uterine adnexectomy (lymph node metastasis is rare, so lymph node dissection is not routine), radiotherapy and chemotherapy and hormone therapy is not yet accurate. But the survival and recurrence are closely affected by sarcoma overgrowth, disease staging, uterine muscle invasion depth, lymphatic metastasis, vascular invasion and so on.
Keywords:AdenosarcomaUterine neoplasmsRare diseasesTherapyPrognosis
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 499-502 )
