Research Progress on the Fertility-Sparing Therapy in Early Cervical Cancer Patients
ZHOU Ying
SHEN Zhen
QIAN Li-li
WU Da-bao
Abstract：Radical hysterectomy and pelvic lymphadenectomy is still the routine treatment for young patients with early cervical cancer, which leads to loss of their fertility. In this review, we retrospectively analyze the latest research progress of vagina and lymph node metastasis after radical surgery of cervical cancer both at home and abroad, finding that only 27%of the patients with early cervical cancer have lymph node metastasis, and then conclude the clinical application prospects of sentinel lymphadenectomy and the research status of"minimal and effective"surgical treatment for fertility-sparing therapy. Sentinel lymph node resection can improve the accuracy of the intraoperative diagnosis of lymph node metastasis, reduces unnecessary excessive treatment, which can be an alternative to the pelvic lymphadenectomy. At present there are 6 kinds of fertility-sparing operations including cervical conization, simple cervical resection, wide resection of the cervical, vaginal radical trachelectomy, laporotomic radical trachelectomy, and laparoscopic robot assisted laparoscopic resection of the cervix. For patients with lesions>2 cm, 3-4 course NACT before operation are recommended, then combine gynecologic examination and radiographic evidence, decide the cervical resection range and choose the operation method.
Keywords：Uterine cervical neoplasmsFertilityNeoplasm metastasisLymph node excision
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 374-380 )