Progress of Exosome in the Pathogenesis, Diagnosis and Treatment of Ovarian Cancer
ZHANG Tao
WANG Xi-peng
Abstract：Ovarian cancer is the highest mortality rate of malignant tumor in gynecologic cancer. Due to the lack of specific markers, the early diagnosis of ovarian cancer is very difficult. In recent years, the exosome has become a hot research topic in many fields,as for its wide distribution,rich content and functional diversity, more and more studies into the field of cancer research. Exosomes can be derived from many kinds of cells and body fluid. They can mediate cell-cell information exchange, promote the occurrence and development of tumors through the delivery of a variety of proteins, lipids, mRNA and miRNA fragments and other biological functions. In addition, due to the specific antigen expression of tumor related exosomes, it provide a new idea for the diagnosis and treatment of tumors. This article reviews researches on the diagnosis and treatment of exosomes in the development and occurrence of ovarian cancer, the mechanism is more precise and more comprehensive in order to reveal the exosomes in ovarian cancer, and provide a theoretical basis for the new treatment methods.
Keywords：ExosomeOvarian neoplasmsCarcinomaDiagnosisTherapy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 23-26 )