Research Progress of Common Gynecologic Malignancy in the Autophagy
WANG Ming-yuan
TANG Xiao-han
LU Mei-song
Abstract：Gynecological malignant tumor is one of the most common malignant diseases of women, which is seriously affecting the health of women, including cervical cancer, endometrial cancer, ovarian cancer, cancers of the vagina and vulva cancer. Among them, cervical cancer, endometrial cancer and ovarian cancer are the most common types. So far, treatment of gynecological tumors usually includes surgery, radiation therapy and chemotherapy. However, the high morbidity and mortality as well as resistance to chemotherapy drugs seriously restrict the cure rates. In recent years, with the development of cancer research, the biological process of autophagy has attracted more attention. Autophagy plays a very important role in the development of common gynecological malignant tumor. In addition, autophagy enhances the chemotherapeutic sensitivity of tumor cell. Furthermore, ovarian cancer, endometrial cancer, cervical cancer and other common gynecological malignant tumor tissues are commonly regulated by autophagy. So, autophagy provides a new way of treatment. And the intervention of autophagy may become a new therapy of gynecologic tumor treatment.
Keywords：AutophagyGenital neoplasmsfemaleUterine cervical neoplasmsEndometrial neoplasmsOvarian neoplasmsBeclin1
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 5-8 )