The Expression of Galectin-1 in Peripheral Blood and Placental Tissue of Preeclampsia Patients and Its Significance
HU Li-fang
LI Lan
HUANG Wen-zhen
LIU Tong
Abstract：Objective:To investigate the expression of galectin-1 in peripheral blood and placental tissue of preeclampsia patients and its significance. Methods:A total of 53 cases of early onset severe preeclampsia and 53 cases of normal pregnant people were selected as research objects. The concentration of serum Gal-1 was detected by ELISA and the expression of Gal-1 protein in placenta tissue was detected by immunohistochemistry. Results:The concentration of serum Gal-1 of the observation group and the control group were (38.59±9.02) ng/L and (27.33±8.31) ng/L, respectively. There was significant differences between the two groups (t=6.684, P<0.001). The expression of Gal-1 protein in observation group was significantly higher than that in the control group (Z=5.632,P<0.001). Conclusions:Gal-1 may be related to the early onset severe preeclampsia. It may be a valuable biomarker for predicting preeclampsia.
Keywords：Pre-eclampsiaGalectin 1Blood chemical analysisPlacenta
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 561-562,573 )