The Action of Immune Cells in the Pathogenesis of Endometriosis
LI Zhuo-li
HAO Min
ZHAO Wei-hong
Abstract:Endometriosis (EMs) is a common gynecologic disease,the prevalence is 10%-15%,and still rising. But the pathogenesis remain unclear. In the multitudinous hypothesis ,the immune theory has drawn more and more attention ,and become a hot research. Recently ,many studies demonstrate that EMs is an immune inflammatory disease. In abdominal cavity , the change of immune cells (macrophages,NK cells,T cells,DC,mast cells) quantity and function can enhance the ability of endometrial cell invasion,adhesion,proliferation,angiogenesis,promote the ectopic lesions growth and maintenance,and made the endometrial cells that reverse into abdominal cavity to escape from immune surveillance.
Keywords:EndometriosisImmunohistochemistryMacrophagesCytokines
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 260-262 )
