Research Progress of MicroRNA-375 in Gynecological Malignant Tumors
ZHANG Li-li
HAO Min
ZHAO Wei-hong
Abstract：MicroRNA-375 is a highly conservative miRNA,which play important roles in suppressing proliferation, promoting apoptosis,suppressing invasion and metastasis by means of regulating the expression of genes. The research has revealed that miR-375 is remarkably down-regulated in many tumor cells and ontic tissues ,and is closely related in cancer development and progression. Recent years ,the research on miR-375 in cervical cancer and endometrial cancer is increasing , but the mechanism should be studied future. This article elaborates biological function of miR-375 and improvements of some studies in gynecological malignant tumors.
Keywords：MicroRNAsNeoplasmsUterine cervical neoplasmsEndometrial neoplasmsCell proliferationApoptosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 229-231,235 )