Research progress on glucocorticoids in the treatment of acute infectious diseases
Sun Lin
Xie Zihui
Deng Ying
Abstract：Glucocorticoids(GCs),characterized by complex mechanisms and broad effects,are commonly used in clinical practice as anti-inflammatory and immunosuppressive agents and can be employed in the treatment of infectious diseases.They effectively alleviate excessive inflammatory responses triggered by infections,mitigate tissue damage,and improve patient symptoms and prognosis.The clinical application of glucocorticoids in treating acute infectious diseases remains a hot topic in research.This review summarizes the therapeutic use of glucocorticoids in common acute infectious diseases,including meningitis,community-acquired pneumonia(CAP),infectious myocarditis,sepsis,and septic shock.It also discusses clinical concerns regarding the safety and adverse effects associated with glucocorticoids therapy.
Keywords：GlucocorticoidsAcute infectionAnti-inflammatory responseCommunity-acquired pneumoniaShock infectionSepsisMeningitisMyocarditis
Publication Date：2025-08-28
Online Publishing Date：2025-09-26(First online date of this platform, not the publication date of the document)
Pages：8( 301-308 )