Effects of repetitiously transcranial magnetic stimulation on serum levels of interlenkin-6 and rehabilitation of nerve function in patients with acute cerebral infarction
Zou Chunying
Jiang Xiaoxue
Yu Fengwei
Abstract：Objective: To investigate the effects of repetitiously transcranial magnetic stimulation (rTMS) on serum interleukin-6 (IL-6) level and rehabilitation of nerve function in patients with acute cerebral infarction (ACI). Methods: Eighty patients with ACI admitted in the First Affiliated Hospital of Jiamusi University were divided into two groups according to the time of visit (40 each). All the patients were treated with routine therapy for ACI. Additionally, patients in control group received sham rTMS stimulation, and those in observation group received rTMS stimulation with appropriative medical magnetic stimulator (coil diameter 9 cm, maximum magnetic field intensity 1.4 T ). The coil was placed vertically on the first somatic movement area of cerebral cortex of the uninjured side, with 60％ of maximum magnetic field intensity and frequency of stimulation 1 Hz, 500 times per day. Changes of serum IL-6 levels and neurological function score (NIHSS) were compared between the two groups. Results: There was no statistical significance in serous IL-6 level and NIHSS score between the two groups before treatment (P>0.05). On the 3rd, 7th and 10th day after treatment, the serous IL-6 level and NIHSS score were significantly lower in observation group than in control group with significant differences (P<0.05). Conclusions: rTMS may decrease the serous IL-6 level, accelerate the recovery of nerve function in patients with ACI, so is worthy of application.
Keywords：Interleukin -6Acute cerebral infarctionRepetitiously transcranial magnetic stimulation
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 158-160 )