Analysis on infection of human papilloma virus in different personal groups

Liu Miao; Zhang Dongqing; Wang Haibin

doi:10.3969/j.issn.1672-8521.2014.04.011

Abstract：Objective:To study the characteristics of human papilloma virus (HPV)infection,such as infection rate,age, gender,subtype distribution,in order to provide the basis of its prevention strategies. Methods:The genotypes of HPV in 1 180 outpatients were detected by real-time multiple fluorescent DNA amplification technology. The infectious characteristics was analyzed. Results:There were 157 HPV-positive patients in 330 male outpatients,among them 101 cases (64.33%) were infected high risk subtypes of HPV,106(67.50%)were infected with low-risk subtype of HPV. In the male HPV in-fection patients,age of 71 patients (46.41%)was 21 to 30 years old,47 (45.19%)aged from 31 to 40 years old,29 (50.00%)aged from 41 to 50 years old,and the age of 10 (66.67%)were above 51 years. In the male patients,the infec-tion rate was the highest in type 39,and followed by types 16 and 59. In 850 cases of female outpatients,HPV were found positive in 243 cases,including 198 cases (81.48%)of high-risk subtypes infection and 79 cases (32.51%)of low-risk sub-type infection. In the female HPV positive patients,the age of 113 patients (41.09%)was 21 to 30 years old,58 patients (21.25%)aged from 31 to 40 years old,43 subjects (24.57%)aged from 41 to 50 years old,24 subjects(26.09%)aged from 50 to 60 years old,and 5 persons(14.29%)were above 61 years old. In female patients,type 58 gave rise to the high-est infection rate,followed by type 16 and 52. Conclusions:Women of the child-bearing age have a high infection rate of HPV,and the age of invasion showed a younger tendency. More attention should be paid to screen HPV infection to married women of 21-30 years old. Screening of HPV in male group should be strengthened,and it may be helpful to reduce the inci-dence and mortality of cervical cancer.