Nursing care and infection management of a patient with sinusoi-dal obstruction syndrome after allogeneic hematopoietic stem cell transplantation under immunosuppression:a case report
Li Wang
Li Zhang
Qian Li
Zhenjun Xi
Qianqian Liu
Chang Liu
Jiemei Jiang
Yueming Wu
Mei Yu
Yongsheng Liu
Xiaobing Li
Abstract：This report summarizes the nursing and infection management process for a patient who developed severe late-onset sinusoidal obstruction syndrome while in a state of deep immunosuppression after allogeneic hematopoietic stem cell transplantation. Key nursing measures included: strict adherence to infection control protocols in the laminar airflow ward during potent immunosuppressive therapy; rigorous aseptic techniques for invasive procedures such as abdominal paracentesis and drainage to prevent catheter-related infections; and enhanced monitoring and differentiation of symptoms like fever and diarrhea to guard against opportunistic infections. Symptom management for sinusoidal obstruction syndrome, nutritional support, and psychological care were implemented concurrently. Through these comprehensive nursing interventions, the patient recovered without developing any severe infections while immunocompromised. This case offers valuable insights into infection prevention and comprehensive care for similar high-risk patients.
Keywords：hematopoietic stem cell transplantationsinusoidal obstruction syndromeinfection controlimmuno-suppressionnursing care
Publication Date：2025-12-30
Online Publishing Date：2026-01-27(First online date of this platform, not the publication date of the document)
Pages：9( 72-80 )