The 2025 Nobel Prize in Physiology or Medicine:a milestone in peripheral
Zheng Wu
Yingmei Feng
Abstract：Immune tolerance research The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their groundbreaking contributions to the field of peripheral immune tolerance. Their discoveries related to regulatory T cells (Tregs) and the FOXP3 gene have fundamentally transformed our understanding of how the immune system distinguishes between foreign invaders and the body's own tissues, opening new avenues for the treatment of autoimmune diseases and other immune-related disorders.
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Publication Date：2025-09-30
Online Publishing Date：2025-12-02(First online date of this platform, not the publication date of the document)
Pages：3( 2-4 )