Recent advances in iron nanomaterials for cancer treatment
YANG Xuanyu
LIN Siqi
ZHANG Qianqian
LIU Yuting
WANG Shuhui
YANG Fen
Abstract：The application and advancement of nanomaterials have addressed numerous challenges in daily life and industrial practices,with their implementation significantly optimizing outcomes.As a global health threat,cancer is characterized by its high incidence,mortality rates,and severe complications.For malignancies of varying types and anatomical locations,personalized engineering of iron-based nanomaterials loaded with specific anticancer drugs enables targeted therapeutic delivery.This strategy not only maximizes medication safety and efficacy for cancer patients but also reduces required dosages,thereby lowering biotoxicity and alleviating adverse reactions.Moreover,through adjustments in surface modification methods,material selection,structural configurations,metal combinations,and drug payloads,iron-based nanomaterials can be tailored to develop diverse therapeutic modalities and protocols.This article therefore presents the advantages of iron-based nanomaterials in tumor treatment,focusing on their capabilities for targeted drug delivery,low-dose precision therapy,and structural-functional versatility,while briefly elaborating on the underlying mechanisms.The discussion aims to provide valuable references for advancing personalized precision medicine utilizing iron-based nanomaterials.
Keywords：iron nanomaterialstumorcell death
Publication Date：2026-02-28
Online Publishing Date：2026-01-28(First online date of this platform, not the publication date of the document)
Pages：12( 97-108 )