Advances in the study of the bacterial phosphotransferase system affecting bacterial biofilms by regulating sugar metabolism
BAI Chunqing
LI Xuemeng
GUO Zhen
LIU Jun
Abstract：Bacterial biofilm(BF)is a complex three-dimensional structure formed by bacteria on the surface of an object that is highly resistant to drugs and environmentally adapted.The formation of BF is an important way for bacteria to adapt to the environment and lead to persistent infections,and its presence poses a serious threat to human health.The bacterial phosphotransferase system(PTS),a key system for bacterial sugar uptake and metabolism of sugars,plays a crucial role in bacterial metabolism and signaling through a unique phosphorylation cascade reaction PTS precisely regulating sugar transport and metabolism,which in turn affects bacterial physiological states and behavioral patterns.This article provides a review of the progress of research on the effects of key components of PTS on its BF in different bacteria.
Keywords：phosphotransferase systembacteriabiofilmsugar metabolism
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 511-517 )