Pathological characteristics of postoperative recurrence and influencing factors of recurrence within 5 years in cervical cancer patients
CHEN Wen-shi
MO Yu
WU Xiao-rong
YI Yan-xi
Abstract：Objective To investigate the pathological characteristics of postoperative recurrence and the influencing factors of recurrence within 5 years in stage Ⅰa 2-Ⅱa 2 cervical cancer patients.Methods Retrospective analysis was performed on clinical data of 375 patients with stage Ⅰa 2-Ⅱa 2 cervical cancer treated in the People's Hospital of Zhanjiang Center from January 2015 to July 2018.The pathological characteristics of postoperative recurrence in stage Ⅰa 2-Ⅱa 2 cervical cancer patients were analyzed.Patients were divided into 5-year recurrence free survival(DFS)group and a recurrence group based on 5-year recurrence data.The influencing factors of recurrence within 5 years were determined by using multivariate logistic regression analysis.Results The 5-year DFS rate was 85.3％.Among the recurrent cases,there were 22 cases(40.0％)of stage Ⅱa 2,38 cases(69.1％)of poorly differentiated type,39 cases(70.9％)of endogenous type lesions,and 37 cases(67.3％)of squamous cell carcinoma.Stage Ⅱa cervical cancer,poorly differentiated cervical cancer,tumors≥4 cm,and cervical infiltration depth>1/2 of the myometrium were independent risk factors for recurrence within 5 years.Conclusion Patients with stage Ⅱa cervical cancer,poorly differentiated cervical cancer,tumors greater than 4 cm,and cervical infiltration depth greater than 1/2 of the myometrium in stage Ⅰa 2-Ⅱa 2 cervical cancer are prone to recurrence within 5 years.
Keywords：stage Ⅰa 2-Ⅱa 2cervical cancerrecurrencepathological characteristics5-year recurrence free survivalinfluence factor
Publication Date：2024-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 302-305 )