Predictive value of ferritin,uric acid,homocysteine,and hypersensitive C-reactive protein for carotid intima-media thickening in primary hypertension
LIN Zi-bo
CHEN Hua-jian
LI Li-shuo
CHEN Hua-tao
Abstract：Objective To investigate the predictive value of ferritin,uric acid,homocysteine(Hcy),and hypersensitive C-reactive protein(hs-CRP)for carotid intima-media thickening(CIMT)in primary hypertension.Methods A total of 106 patients with primary hypertension were divided into thickening group(55 cases)and normal group(51 cases).Ferritin,uric acid,Hcy,and hs-CRP levels were compared between 2 groups and analyzed Logistic regression analysis.Their predictive value for CIMT was evaluated using ROC curve.Results Ferritin,uric acid,Hcy,and hs-CRP levels were higher in thickening group than in normal group(P<0.01).Logistic regression analysis showed that they were independent risk factors for CIMT(P<0.05).The AUC of ferritin,uric acid,Hcy,hs-CRP,and their combination were 0.735,0.802,0.818,0.778,and 0.939(P<0.01),respectively.Conclusion There may be some predictive value of ferritin,uric acid,Hcy,and hs-CRP for CIMT in primary hypertension,with the highest of their combined detection.
Keywords：ferritinuric acidhomocysteinehypersensitivity C-reactive proteinprimary hypertensioncarotid artery intima-media thickness
Publication Date：2024-06-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 281-284 )