Advances on histone lysine methyltransferase in acute myeloid leukemia
SHENG Yi-lin
FAN Xin-zhu
XU Tao
LUO Zhi-long
GAO Yu-ting
Abstract：Acute myeloid leukemia(AML)is a hematologic malignancy derived from hematopoietic stem cells,with treatment difficulty and poor prognosis.Epigenetics plays an important role in the development and progression of leukemia.Histone methylation modification-associated genes and enzymes as therapeutic targets for AML have made great progress.This article briefly reviews the recent research progress of histone H3 lysine methyltransferase in AML.
Keywords：acute myeloid leukemiaepigeneticshistone lysine methyltransferase
Publication Date：2024-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 110-114 )