Application of low-dose head/neck CT angiography and whole brain CT perfusion in carotid-associated cerebral perfusion abnormalities
CAI Pei-kun
CHEN Jie-bin
CAI Yong
LIANG Huan
LIANG Hui-hui
LI Chong-yun
CHEN Xiao-bo
CHEN Xiao-yu
Abstract：Objective To study the application of low-dose head/neck computed tomography angiography(CTA)and whole brain computed tomography perfusion(CTP)in cerebral perfusion.Methods Eighty-six patients with ultrasound-diagnosed carotid artery stenosis(stenosis group)and 50 healthy subjects(control group)underwent low-dose head/neck CTA and whole brain CTP.The cerebral perfusion parameters including cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT)and time to peak(TTP),and distribution of brain functional regions of abnormal CTP parameters were compared between two groups.Results Compared with control group,CBF and CBV in the anterior circulation were lower,while MTT and TTP were higher(P＜0.01)in stenosis group.The percentages of abnormal CBF,CBV,MTT and TTP regions in the whole brain volume were increased with the aggravation of carotid artery stenosis(P-＜0.01).Conclusion Low-dose head/neck CTA and whole brain CTP can be valuable for carotid-associated cerebral perfusion abnormalities.
Keywords：computed tomography angiographycomputed tomography perfusioncarotid artery stenosis
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 631-635 )