Detection and analysis of Cosson value on the whole blood of nude mice hamster and SD rats
BAN Xing-min
ZHOU Lei
HUNG Jian
Abstract：Objective:To detect and analyze the normal hemorheological characteristics of nude mice,hamsters and Sprague-Dawley(SD)rats.Methods:The whole blood viscosity values of nude mice,hamsters and SD rats were tested simultaneously by means of the cone and plate viscometer,and Cosson Viscosity(CV)Cosson yield stress(CY)in the blood among them were calculated with unitary linear regression.Results:The whole blood viscosity at high shear rate,hemotocrit,and rigidity index of erythrocyte among 3 species of animals were similar,and there was a little higher in nude rate but no statistical difference;while there existed a significant difference in the values of whole blood viscosity at low shear rate,plasma viscosity and aggregation index of erythrocyte(P<0.01)among them.and SD rats exhibited the highest values.CV value showed no remarkable difference among 3 groups (P>0.05),whereas substantial difference was found in CY value(P<0.01).Conclusion:The erythrocyte deformability is nearly the same among 3 species of animals,but the erythrocyte aggregation involving many extracellular factors appears a noticeable difference.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 168-169 )