Relationship between P53，nm 23 and PCNA expressions in tissues of squamous cell carcinoma and adenocarcinoma of lung and lymph node metastasis
Abstract：Objective：To study the relationships between P53，nm23 and PCNA expressions in tissues of squamous cell carcinoma and adenocarcinoma of lung and lymph node metastasis．Methods：The expressions of P53，nm23 and PCNA in 86 patients with lung cancer were studied with S-P immunohistochemical methods．Results：The positive expression rates of P53，nm23 and PCNA in tissues of lung cancer were 57．0％，73．3％ and 82．5％ respectively．The expressions of P53 and nm23 in squamous cell carcinoma were not different from those in adenocarcinoma（P53：58．7％ vs 52．2％；nm23：74．6％ vs 69．6％；P＞0．05），while that of PCNA had a significant difference between them（92．1％ vs 56．5％，P＜0．01）．In tissues of lung cancer with or without lymph node metastasis，the positive expression rates of P53，nm23 and PCNA also had no difference（P53：51．1％ vs 51．2％；nm23：88．9％ vs 95．1％；PCNA：80％ vs 90．2％；P＜0．05）．Conclusion：The expressions of P53，nm23 and PCNA in tissues of lung cancer had no relation to lymph node metastasis．
Machine-generated Keywords：
Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 83-84 )