Application analysis of stomach-partitioning gastrojejunostomy in the treatment of pyloric obstruction in locally advanced gastric cancer
HUANG Xin-ming
WU Liu-cheng
QIN Yu-zhou
HUANG Ming-wei
JIN Qin-wen
WANG Ting-an
Abstract：Objective To compare the therapeutic efficacy and prognostic outcomes of stomach-partitioning gas-trojejunostomy(SPGJ)and conventional gastrojejunostomy(CGJ)in patients with locally advanced gastric cancer compli-cated by pyloric obstruction.Methods A retrospective analysis was conducted on clinical data from 100 patients with lo-cally advanced gastric cancer and pyloric obstruction treated at the Department of Gastrointestinal Surgery,Affiliated Canc-er Hospital of Guangxi Medical University between January 2018 and September 2024.Thirty-eight patients underwent SPGJ(SPGJ group),and sixty-two underwent CGJ(CGJ group).Preoperative baseline characteristics,operative time,intraoperative blood loss,postoperative complications,recovery of bowel function,time to oral intake,nutritional indica-tors,and postoperative outcomes were compared between the two groups.Results Compared with the CGJ group,pa-tients in the SPGJ group demonstrated significantly faster recovery to full and semi-liquid diets(t=-2.787,P=0.007;t=-1.999,P=0.049),shorter times to first flatus/defecation and nasogastric tube removal(t=-2.446,P=0.016;t=-2.448,P=0.016),better postoperative 1-month weight maintenance(Z=-2.034,P=0.042),higher minimum levels of serum total protein and albumin within 1 month postoperatively(t=2.643,P=0.010;t=2.336,P=0.022),lower rates of reoperation due to complications(x2=3.912,P=0.048),and improved performance status scores(x2=17.481,P=0.002).Conclusion For patients with locally advanced gastric cancer complicated by pyloric obstruction,SPGJ offers significant advantages over CGJ and may be considered the preferred surgical option.
Keywords：gastric cancerpyloric obstructiongastrojejunostomystomach-partitioning gastrojejunostomyprognosis
Publication Date：2025-09-15
Online Publishing Date：2025-11-06(First online date of this platform, not the publication date of the document)
Pages：7( 1316-1322 )