Research progress of mesenchymal stem cell therapy in pulmonary hypertension
DONG Zhi-hui
RAO Shu-ke
XIE Chen-li
XU Gui-hua
Abstract：Pulmonary hypertension(PH)is a clinical pathophysiological syndrome characterized by a progressive increase in pulmonary vascular resistance and is often associated with various disease complications.Mesenchymal stem cells(MSCs)possess unique properties,including the ability to home to damaged tissues,repair functionality,and par-ticipate in the regulation of systemic inflammation and immune responses,making them a promising candidate for clinical applications.This article reviews recent preclinical studies on the application of MSCs in the treatment of pulmonary hyper-tension,aiming to provide scientific evidence for future clinical practices.
Keywords：pulmonary hypertensionmesenchymal stem cellsextracellular vesicles
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1544-1548 )