Imaging characteristics and clinical application value of infrared thermal imaging in a rat model of slow femoral venous blood flow

CHEN Wei-yi; ZHANG Yong-bin; SU Jia-qi; LIN Wei-guo; RUAN Wei; DENG Fang-ge

doi:10.13820/j.cnki.gdyx.20240588

Abstract：Objective To explore the imaging characteristics and clinical application value of infrared thermal imaging in a rat model of slow femoral venous blood flow.Methods Twelve Sprague-Dawley rats were randomly divided into two groups:the epinephrine group(model group)and the saline group(control group).The model group received 1 mg/mL epinephrine injections,while the control group received an equal volume of saline,administered twice.Two hours after the first injection,the rats were made to swim in ice water for 5 minutes.Infrared thermal imaging was used to meas-ure the temperature of both sides of the femoral triangle region before and after modeling.Blood samples were collected from the abdominal aorta to test coagulation indicators and IL-6 levels,and the right femoral vein was subjected to patho-logical examination.Results In the model group,activated partial thromboplastin time(APTT)(P＜0.01)and throm-bin time(TT)(P＜0.01)were significantly shorter than those in the control group,and IL-6 levels were higher(P=0.02).Histological examination of femoral vein sections showed normal vascular morphology with no clear inflammation or thrombosis.The highest pre-modeling temperature in the femoral triangle region of the model group was(35.34±0.47)℃,and post-modeling was(36.57±0.94)℃,showing a statistically significant difference(P＜0.01).The post-modeling highest temperature in the model group was higher than that in the saline group(P＜0.01).Conclusion Infra-red thermal imaging of the rat model of slow femoral venous blood flow shows relatively high temperatures.With its non-invasive and radiation-free advantages,infrared thermal imaging can serve as an auxiliary diagnostic tool for slow blood flow conditions.