Correlations between Crouse score,IMT,and the degree of valve calcification in elderly calcific heart valve dis-ease patients
CAI Jun
ZHANG Fu-shan
ZHANG Wei-feng
Abstract：Objective To explore the relationship between Crouse Score,intima-media thickness(IMT),and the degree of valve calcification in elderly patients with calcific heart valve disease.Methods A retrospective analysis was conducted on the clinical data of 106 elderly patients with calcific heart valve disease from April 2020 to March 2023(Observation group).Additionally,90 patients with carotid atherosclerosis without heart valve disease were selected as control group 1,and 95 non-elderly patients with calcific heart valve disease were selected as control group 2.Single-factor analysis of variance was used to compare Crouse Score,IMT,luminal stenosis,and Crouse Score and IMT in pa-tients with different degrees of valve calcification in calcific heart valve disease.Pearson analysis was employed to explore the correlation between Crouse Score,IMT,and the degree of valve calcification.ROC curve analysis was performed to e-valuate the predictive value of Crouse Score and IMT for valve calcification in elderly patients with calcific heart valve dis-ease.Results Crouse Score,IMT,and luminal stenosis in the observation group were significantly higher than those in control group 1 and control group 2(P＜0.05).For patients with different degrees of valve calcification in calcific heart valve disease,Crouse Score and IMT were compared as follows:Grade 1＜Grade 2＜Grade 3(P＜0.05).The corre-lation analysis results showed that Crouse Score and IMT were positively correlated with the degree of valve calcification in elderly patients with calcific heart valve disease(r=0.585,0.623,P＜0.05).The ROC curve demonstrated that the AUC of the joint prediction of Crouse Score and IMT for valve calcification in elderly patients with calcific heart valve dis-ease was 0.802(95％CI:0.738-0.867),significantly higher than the AUC for individual predictions,with optimal di-agnostic sensitivity and specificity of 0.887 and 0.794,respectively(P＜0.05).Conclusion Crouse Score and IMT are abnormally elevated in elderly patients with calcific heart valve disease and are positively correlated with the degree of valve calcification.Measurement of these indicators assists in the assessment of heart valve calcification levels.
Keywords：elderly calcific heart valve diseasecarotid artery plaque scorecarotid artery intima-media thick-nessvalve calcification
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 463-466 )