Short-term efficacy of Lingze tablet combined with tamsulosin hydrochloride on the treatment of benign prostat-ic hyperplasia
CHEN Shao-feng
GENG Qiang
LI Chun-xu
LI Chong
SUN Yuan
ZHAO Yu
Abstract：Objective To investigate the short-term efficacy of Lingze tablet combined with tamsulosin hydro-chloride on the treatment of patients with benign prostatic hyperplasia(BPH).Methods Eighty-six cases of senile pa-tients with benign prostatic hyperplasia were divided into control group(43 cases)and observation group(43 cases).The control group received oral administration of tamsulosin hydrochloride capsules,while the observation group received tam-sulosin hydrochloride capsules and Lingze tablets.The treatment lasted for 12 weeks.The efficacy of the two groups was compared using the International Prostate Symptom Score(IPSS),Quality of Life(QOL)score,post-void residual urine volume(PVR),maximum urine flow rate(Qmax),prostate volume(PV),total prostate-specific antigen(tPSA)levels,free prostate-specific antigen(fPSA)levels,as well as interleukin(IL)-6 and tumor necrosis factor-alpha(TNF-α)levels.Results The total effective rate in the observation group was higher than that in the control group(P＜0.05).After treatment,both the IPSS and QOL scores,PVR,PV,IL-6,TNF-α levels,and fPSA and tPSA levels of patients in both the control and observation groups decreased compared to before treatment(P＜0.05).After treatment,the Qmax of patients in both the control and observation groups increased compared to before treatment(P＜0.05).Conclusion Lingze tablets,in combination with tamsulosin hydrochloride,can reduce inflammatory responses in patients with BPH,improve clinical indicators,and enhance prostate function.
Keywords：benign prostatic hyperplasiaLingze tablettamsulosin hydrochlorideshort-term curative effect
Publication Date：2024-02-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 183-187 )