Clinical observation of self-formulated Shu Jin Huo Xue Tang as an adjunct to arthroscopic tibial tuberosity osteotomy

HUANG Yong-hua; LI Shu-liang; WANG Yu-xi

doi:10.13820/j.cnki.gdyx.20223512

Abstract：Objective To observe the clinical effects of a self-formulated Shu Jin Huo Xue Tang as an adjunct to arthroscopic tibial tuberosity osteotomy.Methods A retrospective analysis was conducted on the clinical data of 84 patients who underwent arthroscopic-assisted tibial tuberosity osteotomy in orthopedic department from January 2019 to June 2020.The patients were randomly divided into an experimental group and a control group,with 42 cases in each.Two cases dropped out from each group,leaving a final completion of 40 cases in each group.Both groups underwent ar-throscopic-assisted medial open-wedge tibial osteotomy with proximal medial"T"compression locking plate fixation.The experimental group started taking Shu Jin Huo Xue Tang from the first day after surgery,three times a day,for a total of 14 days.Pain improvement,knee joint function,and postoperative complications were assessed on postoperative days 3,1 month,and 3 months.Results The excellent rate of surgery in the experimental group(90.00％)was higher than that in the control group(70.00％)(P=0.025).There was no statistically significant difference in surgical time and in-traoperative blood loss between the two groups(P＞0.05).The length of hospital stay in the experimental group was shor-ter than that in the control group(P＜0.05).There was no statistically significant difference in preoperative VAS scores between the two groups(P＞0.05).The VAS scores gradually decreased at postoperative day 3,1 month,and 3 months,with the experimental group having lower VAS scores than the control group(P＜0.05).There was no significant differ-ence in preoperative serum D-dimer(D-D)and high-sensitivity C-reactive protein(hs-CRP)levels between the two groups(P＞0.05).The levels of D-D and hs-CRP in both groups decreased at 3 months postoperatively,with the experimental group being lower than the control group(P＜0.05).There was no statistically significant difference in pre-operative HSS scores between the two groups(P＞0.05).The HSS scores gradually increased at postoperative day 3,1 month,and 3 months,with the experimental group having higher HSS scores than the control group(P＜0.05).There were no infections,heterotopic ossifications,or re-fractures at the osteotomy site in either group,and no cases required reoperation.The incidence of deep vein thrombosis in the lower limbs was 5.00％in the experimental group,significantly lower than that in the control group(17.50％)(P＜0.05).Conclusion The use of the self-formulated Shu Jin Huo Xue Tang in the perioperative period of arthroscopic-assisted tibial tuberosity osteotomy significantly improves the effica-cy,effectively relieved postoperative pain symptoms in patients with knee arthritis,promoted the recovery of knee joint function,alleviates systemic inflammatory reactions,improves hemorheology,and reduces the incidence of complications.