Predictive value of systemic inflammation response index for stroke-associated pneumonia in patients with acute intracerebral hemorrhage
DU Zhen-ping
LI Hui-ping
DU Ya-ming
WANG Li-xin
LU Hong-ji
Abstract：Objective To evaluate the predictive value of the systemic immune-inflammation Index(SII)for the occurrence of stroke-associated pneumonia(SAP)in patients with intracerebral hemorrhage(ICH).Methods A retrospective analysis was conducted on 241 patients with acute intracerebral hemorrhage admitted to the Second Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2019 to May 2020.Patients were divided into the SAP group(83 cases)and non-SAP group(158 cases)based on the occurrence of SAP.Demographic characteristics,medi-cal history,and complete blood count results were collected.The SII value was calculated,and logistic regression analy-sis,both univariate and multivariate,was employed to determine the independent correlation between SII and SAP.The predictive value of SII was evaluated using indicators such as area under the curve(AUC),sensitivity,and specificity in the ROC curve.Results Among the 241 patients with intracerebral hemorrhage,83(34.4％)developed pneumonia.Univariate analysis showed that patients in the SAP group had higher bleeding volume,admission National Institutes of Health Stroke Scale(NHISS),admission Glasgow Coma Scale(GCS),Watada water swallow test grade,and SII com-pared to the non-SAP group.The proportion of patients undergoing neurosurgical treatment was higher in the SAP group,and the differences between the groups were statistically significant(P＜0.05).Multivariate analysis results showed that compared to the first quartile of SII,the odds ratios(ORs)(95％CI)for SAP risk in the third and fourth quartiles were 3.40(1.18-9.78)and 5.20(1.81-14.95),respectively,with statistically significant differences(P＜0.05).ROC curve analysis demonstrated an area under the curve of 0.708(P＜0.001).The optimal cutoff point for SII was 2 071.95 x 109,with a sensitivity of 54.2％and specificity of 77.8％for predicting SAP in ICH patients.Conclusion SII is an in-dependent risk factor for the occurrence of SAP in ICH patients and is associated with adverse outcomes.
Keywords：systemic immune-inflammation indexintracerebral hemorrhagestroke-associated pneumoniapredictionrisk factors
Publication Date：2023-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1430-1434 )