Association between blood pressure control and autonomic nervous function in hypertensive patients
WU Shi-wei
YU Yi-jun
GU Li
XU Yan-ling
WU Hui-jun
ZHENG Wei
ZHOU Zhi-yun
ZOU Wu-song
GU Ye
Abstract：Objective To investigate the effect of blood pressure (BP) control on cardiac autonomic nervous function by researching the correlation between BP control and heart rate recovery (HRR) and heart rate variability (HRV) in hypertensive patients.Methods Hypertensive patients, who were hospitalized in the department of cardiology during October 2016 to September 2017, were grouped into controlled BP group (n=71) and uncontrolled BP group (n=50) for retrospective study. HRR, HRV and clinical characteristics of the two groups were analyzed.Results Smoker, calcium antagonist use and combined drug treatment were significantly higher in the uncontrolled BP group than in the controlled BP group (P＜0.05). HRR and HRV values (rMSSD, pNN50, VLF, LF and HF) were significantly lower in the uncontrolled BP group than in the controlled BP group (P＜0.01). Multiple logistic regression analysis showed that lower HRV values (rMSSD, pNN50, VLF, LF and HF) were risk factors for BP control of hypertension after adjusting for smoker and calcium antagonist use. Conclusion The present results demonstrate that uncontrolled BP is associated with lower HRR and HRV values, suggesting that impaired autonomic nerve function is more serious in patients with uncontrolled hypertension.
Keywords：hypertensionheart rate recoveryheart rate variabilityautonomic nervous function
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 671-675 )